2,6-dichloro-5-cyano-3-Pyridinecarboxylic acid ethyl ester - Names and Identifiers
Name | 3-Pyridinecarboxylic acid, 2,6-dichloro-5-cyano-, ethyl ester
|
Synonyms | Ethyl 2,6-Dichloro-5-cyanonicotinate Ethyl 2,6-dichloro-5-cyanopyridine-3-carboxylate 2,6-dichloro-5-cyano-3-Pyridinecarboxylic acid ethyl ester 3-Pyridinecarboxylic acid, 2,6-dichloro-5-cyano-, ethyl ester 3-Pyridinecarboxylic acid, 2,6-dichloro-5-cyano-, ethyl este...
|
CAS | 919354-52-2
|
2,6-dichloro-5-cyano-3-Pyridinecarboxylic acid ethyl ester - Physico-chemical Properties
Molecular Formula | C9H6Cl2N2O2
|
Molar Mass | 245.06 |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
2,6-dichloro-5-cyano-3-Pyridinecarboxylic acid ethyl ester - Introduction
3-Pyridinecarboxylic acid, 2,6-dichloro-5-cyano-, ethyl ester, also known as 3-picolinic acid, 2,6-dichloro-5-cyanoethyl ester, is an organic compound.
Nature:
-Appearance: 3-Pyridinecarboxylic acid, 2,6-dichloro-5-cyano-, ethyl ester is a colorless to pale yellow liquid.
-Solubility: It is soluble in organic solvents, such as alcohols, ethers and ketones, and insoluble in water.
Use:
- 3-Pyridinecarboxylic acid, 2,6-dichloro-5-cyano-, ethyl ester can be used as a reagent in organic synthesis and is widely used in the fields of pharmacy, pesticide and dye.
-It can be used as an intermediate for the synthesis of drugs and pesticides, and used to synthesize biologically active compounds.
Method:
3-Pyridinecarboxylic acid, 2,6-dichloro-5-cyano-, ethyl ester is usually synthesized by the following steps:
1. First, 3-picolinic acid and thionyl chloride are reacted in an appropriate solvent at a low temperature.
2. Then, thionyl chloride and a dehydrating agent are added to the reaction mixture, and the reaction is carried out at an appropriate temperature.
3. finally, add acidic solution and extract the organic phase, and obtain pure 3-Pyridinecarboxylic acid, 2,6-dichloro-5-cyano-, ethyl ester by distillation separation.
Safety Information:
3-Pyridinecarboxylic acid, 2,6-dichloro-5-cyano-, ethyl ester is an organic compound, so appropriate safety measures need to be taken when handling. It may be toxic and irritating to the human body, so direct contact with skin, eyes and respiratory tract should be avoided when using it. Operate in a well-ventilated area and wear appropriate protective equipment such as gloves, goggles and protective masks. When using and storing, please follow the safety procedures and store it in a safe and sealed container, away from fire and oxidizing agents.
Last Update:2024-04-09 21:01:54